Factory directly provide Paeoniflorin for Greenland Manufacturer

Factory directly provide
 Paeoniflorin for Greenland Manufacturer

Short Description:

A. Basic information 【Product name】 Paeoniflorin 【Source of plant】 Paeonia albiflora Pall 【Active ingredients】 Paeoniflorin 【Specifications】 Paeoniflorin40%,95%;OEM 【Extraction solvent】 Ethanol B. Main functions a) Reduce blood pressure and rheumatoid factor titer, to anti-inflammatory and immunomodulatory action。 b) Inhibits sympathetic nerve excitability, to antispasmodic, analgesic and anticonvulsant。 c) Protect liver...


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During the past few years, our business absorbed and digested state-of-the-art technologies the two at home and abroad. Meanwhile, our firm staffs a group of experts devoted to your development of Luci Ganoderma Extract , Anti Oxidation , Paeonia Albiflora Extract , For even more inquires make sure you will not wait to make contact with us. Thank you - Your help continuously inspires us.
Factory directly provide Paeoniflorin for Greenland Manufacturer Detail:

A. Basic information

Product name

Paeoniflorin

Source of plant

Paeonia albiflora Pall

Active ingredients

Paeoniflorin

Specifications

Paeoniflorin40%95%OEM

Extraction solvent

Ethanol

B. Main functions

a) Reduce blood pressure and rheumatoid factor titer, to anti-inflammatory and immunomodulatory action

b) Inhibits sympathetic nerve excitability, to antispasmodic, analgesic and anticonvulsant

c) Protect liver and lowering blood pressure, increase the nutritional blood flow; expand coronary arteries and increases coronary blood flow, preventing platelet aggregation and inhibit cardiac and cerebral vascular diseases

C. Quality key points

Ø Raw material control     SY.png

Ø Residual solvents

D. Quality control and product advantages

Organic raw herbs

QA&QC systemStrictly executing documented procedure prevention management, quality assured.

Technical advantageSharing of professional product identification techniques

Various specifications, OEM accepted

E. Product specifications

Content of active ingredient

Paeoniflorin

Specification

Assayspecification

95%

Item

Testing Standard

Testing method

Character

Appearance

White powder, bitter, sour and astringent

Sensory evaluation

Identification

TLC

confirm

ChP<0502>

HPLC

confirm

ChP<0512>

Assay

Paeoniflorin%

NLT 40%

ChP<0512>

Examination

Loss on drying%

NMT 5.0

ChP<0841>

Ash%

NMT 5.0

ChP<0831>

Heavy metals

LeadPb

NMT 3.0 ppm

ChP<2321>

CadmiumCd

NMT 0.3 ppm

ChP<2321>

MercuryHg

NMT 0.2 ppm

ChP<2321>

ArsenicPb

NMT 2.0 ppm

ChP<2321>

Pesticide residues

Methanol

NMT 100ppm

ChP<0861>

Ethanol

NMT 1000ppm

ChP<0861>

Microorganism

Total aerobic bacteriacfu/g

NMT 1000

ChP<1105>

Mould & Yeastcfu/g

NMY 100

ChP<1105>

Escherichia coli/10g

Not Detected

ChP<1106>

Salmonella/10g

Not Detected

ChP<1106>


Product detail pictures:

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 Paeoniflorin for Greenland Manufacturer detail pictures


Our firm sticks on the theory of "Quality will be the life in the enterprise, and status could be the soul of it" for Factory directly provide Paeoniflorin for Greenland Manufacturer, The product will supply to all over the world, such as: Mauritius , Sweden , Germany , We're always creating new technology to streamline the production, and supply goods with competitive prices and high quality! Customer satisfaction is our priority! You can let us know your idea to develop unique design for your own model to prevent too much similar parts in the market! We will present our best service to satisfy all your needs! You should contact us right away!



  • © 2011 SENS Foundation – http://www.sens.org

    The Fifth SENS conference – James Kirkland

    Author: J.L. Kirkland
    Mayo Clinic

    Adipose tissue is at the nexus of processes involved in healthspan and metabolic dysfunction. Progression of age-related fat tissue dysfunction follows different trajectories across different fat depots, with fat becoming redistributed from subcutaneous to intra-peritoneal depots and ultimately ectopic sites, such as liver, muscle, and bone marrow. This is associated with insulin resistance, hypertension, atherosclerosis, strokes, myocardial infarction, cancer, and cognitive dysfunction. The preadipocytes from which new fat cells develop throughout the lifespan switch into a pro-inflammatory, tissue-remodeling state in old age, instead of differentiating into fat cells. In cellular senescence, proliferation becomes arrested and cells acquire a pro-inflammatory senescent secretory phenotype (SASP), with release of chemokines, cytokines, and extracellular matrix proteases. We found that chronological aging, obesity, progeroid states, and serial subculturing result in accumulation of senescent preadipocytes with impaired adipogenesis and a pro-inflammatory phenotype. Senescent cells accumulate to a greater extent in subcutaneous than intraperitoneal fat. TNF alpha and IL-6, which increase in fat tissue with aging and obesity, can induce preadipocyte cellular senescence and pro-inflammatory cytokine and chemokine secretion, potentially spreading senescence from cell to cell. We found that growth hormone/IGF-1 pathway mutations that extend lifespan and delay onset of age-related dysfunction in mice also delay fat redistribution, preadipocyte dysfunction, and cellular senescence, particularly in more IGF-1-responsive subcutaneous fat. We propose a model in which metabolic stress or repeated preadipocyte replication with aging cause cellular senescence in a fat depot-dependent manner, with inflammatory cytokine and chemokine generation, immune response activation, and failure to sequester lipotoxic fatty acids. This model is consistent with recent concepts about cellular senescence as being a stress-responsive, adaptive phenotype that entails metabolic and secretory readjustments. Senescent cells in adipose tissue could have profound clinical consequences because of their pro-inflammatory secretory phenotype, the large amount of adipose tissue in humans, and its central metabolic role.



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